CELL-FREEZE® - Cryogenic Storage Container

Charter Medical’s Cell-Freeze® cryogenic storage containers are designed for storage, preservation and transfer of peripherally derived stem cell applications.

Cell-Freeze® Design offers:

• Unique bag film container material remains flexible at ultra low temperatures (-196°C).
• Proprietary membrane port design and attached cap minimizes exposure
• Attached label offers ease of use and traceability in labeling

Features and Benefits

• Polyolefin Film - Specifically selected for it’s low temperature properties
  while maintaining flexibility and clarity when filled with liquid.
• Membrane Port - The attached cap snaps into place to protect the contents
  and minimize exposure during use.
• Attached Label - Supports adherence of computer generated labels
  and allows manual data entry area. Critical information can be viewed quickly by simply opening the freezing cassette.
• Integral Fill Tube - The unique manufacturing method used to secure the fill
  tube to the container body eliminates the need for pvc interfaces with the liquid nitrogen storage section of the container.
• Interface/Connectors - Compatible with sterile connection technology and smart seal technology (Sebra® Model 1100 tube welder). Fits in a variety of freezing cassette systems.

Product Catalog - CELL-FREEZE®

Products

Physical Integrity

The physical integrity of the containers were evaluated for their ability to withstand temperature variations experienced during routine storage of hematopoietic cell products. All containers passed the physical integrity tests performed, which included the initial pressure test and leak tests and the microbial challenge and dye  immersion tests.

Cell Quality

Cell quality was assessed on Cell-Freeze® cryogenic storage containers using diluted HPC with 10% DMSO. All containers met the acceptance requirement for MNC and CD34+ cell recovery of ≥ 70% relative to cell counts of the sample before cryopreservation. The average of MNC and CD34+ cell recoveries were 81% and 84%, respectively. All containers met ≥ 1 CFU acceptance criteria with an average of 78% recovery.